Halozyme inks drug development deal with Pfizer






SAN DIEGO (AP) — Halozyme Therapeutics Inc. said Friday it has reached an agreement with Pfizer to develop injectable versions of the drugmaker’s biotech drugs.


Halozyme specializes in a recombinant hyaluronidase enzyme technology, which is designed to temporarily break down a substance in the body that forms a barrier between cells so drugs can be absorbed faster. That would allow some drugs to be delivered by an injection instead of an IV drip.






Under the terms of the agreement, Halozyme of San Diego has granted to Pfizer, based in New York, a license to develop and release up to six products using its enzyme technology. Halozyme will receive an initial payment of $ 8 million, which includes the upfront fee for exclusive licenses to two specified drugs in primary care and specialty care, and the right for Pfizer to choose up to four additional targets after additional payments.


Halozyme is entitled to additional payments of up to $ 507 million if Pfizer’s products reach certain regulatory and sales milestones. The company is also entitled to additional royalty payments on sales of the drugs.


Shares of Halozyme surged 26 percent, or $ 1.45, to $ 6.97 in midday trading Friday. Pfizer shares slipped 32 cents to $ 25.11 as the broader markets declined.


Medications/Drugs News Headlines – Yahoo! News





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Boehner: Still hope on cliff deal









John Boehner: “It is not the outcome I wanted, but it was the will of the House”



Republicans will keep working to avoid the so-called “fiscal cliff” of tax rises and spending cuts, House Speaker John Boehner has said.


Earlier, right-leaning Republicans rejected a plan by Mr Boehner to raise taxes on higher earners.


Mr Boehner said his party would keep working to break the deadlock but “significant spending cuts and real tax reforms” were needed.


The White House said it would work with Congress to strike a deal.


Analysts say the rejection has weakened Mr Boehner’s position in negotiations with the Obama administration.


Mr Boehner’s plan would have had little chance of passing a Senate vote, but was seen as an effort to tell the US public that the Republicans should not be blamed if a deal could not be reached ahead of the 1 January deadline.


The House is controlled by the Republicans, but the Senate is Democrat-led.


God only knows


Continue reading the main story

Start Quote



What happens now depends on whether President Obama’s foot soldiers are as willing to play chicken with the recovery as Mr Boehner’s troops seem to be”



End Quote


At a press conference, Mr Boehner conceded the House’s failure to take up the tax bill was “not the outcome that I wanted”.


He admitted that “God only knows” how the cliff would be avoided but Republicans would keep working on a plan to protect families and small businesses.


He added: “We only run the House. Democrats continue to run Washington.”


If politicians fail to agree new fiscal rules by the end year, steep tax rises and deep spending cuts are meant to take effect automatically.


Analysts say the resulting “fiscal cliff” could take the US into recession.


Despite the failure of Mr Boehner’s proposal, major European stock markets fell, but by only about 0.5%, as most analysts had expected this to be a long drawn-out process.


The White House said President Barack Obama would work with Congress “to get this done”.


“We are hopeful that we will be able to find a bipartisan solution quickly that protects the middle class and our economy,” it said.


Continue reading the main story

What is the fiscal cliff?


  • On 1 January 2013, tax increases and huge spending cuts are due to come into force – the so-called fiscal cliff

  • Deadline was put in place in 2011 to force president and Congress to agree ways to save money over the next 10 years

  • Fear is that raising taxes while massively cutting spending will have huge impact on households and businesses

  • Experts believe it could push the US into recession, and have a global impact on growth


The House of Representatives is not expected to meet until after Christmas, while the Senate was due to meet only briefly on Friday.


Although Mr Boehner’s proposal would have ensured a tax cut for 99.8% of Americans, it would have imposed a rise on those earning more than $ 1m (£600,000).


Mr Boehner said he had been unable to garner sufficient votes to secure passage of the bill.


Mr Obama initially sought tax rises for those earning more than $ 250,000, but later offered a compromise threshold of $ 400,000.


He also offered a change to the way Social Security cost of living adjustments are made for some recipients, cuts from government healthcare programmes and a two-year extension of the debt ceiling.


‘Non-starters’


Mr Boehner announced his bill on Tuesday, saying he would bring forward a measure that extended Bush-era tax cuts for those earning less than $ 1m per year – but would not address the automatic spending cuts.


Continue reading the main story

Start Quote



Mr Boehner has no alternative but to return to negotiations with Obama, his moral authority shredded but his bargaining hand curiously strengthened”



End Quote



On Wednesday, the Republican leadership added a companion bill that would replace the automatic cuts with a proposal to remove cuts from defence and government operating budgets. They would be offset by reductions elsewhere in the budget.


The proposal would cut food stamps, benefits for federal workers and some social services programmes.


That bill was narrowly passed.


Senate Majority Leader Harry Reid said Mr Boehner’s plans were “non-starters in the Senate”, while White House spokesman Jay Carney called them a “multi-day exercise in futility at a time when we do not have the luxury of exercises in futility”.


Analysts have painted a grim picture of the consequences of going over the cliff, with some warning that the impact could push the US back into recession.


The Organisation for Economic Co-operation and Development (OECD) said in its latest economic outlook that the recession from the cliff could become global.

















































































Changing taxation across the years


Tax year1993-2000200120022003-20082009-20122012 tax brackets2013 scenarios

Source: Tax Foundation, IRS


Tax brackets shown for unmarried individuals



President


fd9b6   64870078 clinton Boehner: Still hope on cliff deal

Bill Clinton


fd9b6   64881479 bush gettylong Boehner: Still hope on cliff deal

George W Bush


fd9b6   64870080 obamabbc Boehner: Still hope on cliff deal

Barack Obama



Tax cuts expire



Tax cuts expire for top incomes



Bottom rate



15%



15%



10%



10%



10%



Up to


$ 8,700



15%



10%



15%



15%



15%



$ 8,700-$ 35,350



15%



28%



27.5%



27%



25%



25%



$ 35,350- $ 85,650



28%



25%



31%



30.5%



30%



28%



28%



$ 85,650- $ 178,650



31%



28%



36%



35.5%



35%



33%



33%



$ 178,650-$ 388,350



36%



33%



36%



Top rate



39.6%



39.1%



38.6%



35%



35%



Over


$ 388,350



39.6%



39.6%



BBC News – Business





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Italy PM Monti resigns, elections likely in February






ROME (Reuters) – Italian Prime Minister Mario Monti tendered his resignation to the president on Friday after 13 months in office, opening the way to a highly uncertain national election in February.


The former European commissioner, appointed to lead an unelected government to save Italy from financial crisis a year ago, has kept his own political plans a closely guarded secret but he has faced growing pressure to seek a second term.






President Giorgio Napolitano is expected to dissolve parliament in the next few days and has already indicated that the most likely date for the election is February 24.


In an unexpected move, Napolitano said he would hold consultations with political leaders from all the main parties on Saturday to discuss the next steps. In the meantime Monti will continue in a caretaker capacity.


European leaders including German Chancellor Angela Merkel and European Commission President Jose Manuel Barroso have called for Monti’s economic reform agenda to continue but Italy’s two main parties have said he should stay out of the race.


Monti, who handed in his resignation during a brief meeting at the presidential palace shortly after parliament approved his government’s 2013 budget, will hold a news conference on Sunday at which he is expected clarify his intentions.


Ordinary Italians are weary of repeated tax hikes and spending cuts and opinion polls offer little evidence that they are ready to give Monti a second term. A survey this week showed 61 percent saying he should not stand.


Whether he runs or not, his legacy will loom over an election which will be fought out over the painful measures he has introduced to try to rein in Italy’s huge public debt and revive its stagnant economy.


His resignation came a couple of months before the end of his term, after his technocrat government lost the support of Silvio Berlusconi‘s centre-right People of Freedom (PDL) party in parliament earlier this month.


Speculation is swirling over Monti’s next moves. These could include outlining policy recommendations, endorsing a centrist alliance committed to his reform agenda or even standing as a candidate in the election himself.


The centre-left Democratic Party (PD) has held a strong lead in the polls for months but a centrist alliance led by Monti could gain enough support in the Senate to force the PD to seek a coalition deal which could help shape the economic agenda.


BERLUSCONI IN WINGS


Senior figures from the alliance, including both the UDC party, which is close to the Roman Catholic Church, and a new group founded by Ferrari sports car chairman Luca di Montezemolo, have been hoping to gain Monti’s backing.


He has not said clearly whether he intends to run, but he has dropped heavy hints he will continue to push a reform agenda that has the backing of both Italy’s business community and its European partners.


The PD has promised to stick to the deficit reduction targets Monti has agreed with the European Union and says it will maintain the broad course he has set while putting more emphasis on reviving growth.


Berlusconi’s return to the political arena has added to the already considerable uncertainty about the centre-right’s intentions and increased the likelihood of a messy and potentially bitter election campaign.


The billionaire media tycoon has fluctuated between attacking the government’s “Germano-centric” austerity policies and promising to stand aside if Monti agrees to lead the centre right, but now appears to have settled on an anti-Monti line.


He has pledged to cut taxes and scrap a hated housing tax which Monti imposed. He has also sounded a stridently anti-German line which has at times echoed the tone of the populist 5-Star Movement headed by maverick comic Beppe Grillo.


The PD and the PDL, both of which supported Monti’s technocrat government in parliament, have made it clear they would not be happy if he ran against them and there have been foretastes of the kind of attacks he can expect.


Former centre-left prime minister Massimo D’Alema said in an interview last week that it would be “morally questionable” for Monti to run against the PD, which backed all of his reforms and which has pledged to maintain his pledges to European partners.


Berlusconi who has mounted an intensive media campaign in the past few days, echoed that criticism this week, saying Monti risked losing the credibility he has won over the past year and becoming a “little political figure”.


(Additional reporting by Gavin Jones, Massimiliano Di Giorgio and Paolo Biondi; Writing by Gavin Jones and James Mackenzie; Editing by Michael Roddy)


World News Headlines – Yahoo! News





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Acer will beat Google to market with its own $99 tablet









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The Benghazi Report and Parents of Children With Mental Illness: Today’s Qs for O’s WH, 12/20/12






TAPPER: Has the president read the Accountability Review Board report?


CARNEY: I don’t know. I haven’t – I know he has been briefed on it. I don’t know if he’s read it word for word, but he’s a voracious reader, so he may have.






TAPPPER: The – I believe one person has resigned and three have been – stepped down from their current duties but are still State Department employees. There might – there might have been an update for that since I last read about that. Is that sufficient for the president? Is that – is that enough accountability from the Accountability Review Board?


CARNEY: I think by every measure, the report has been assessed to be – to have been sharply critical and very blunt and clear-eyed about both problems that exist, problems that need to be fixed and the need for accountability, and actions are – already have been taken, as you just – as you just noted.


TAPPER: I’m not questioning the report. I’m -


CARNEY: Well, again, I think -


TAPPER: I’m wondering: is that enough?


CARNEY: I think independent experts here, Admiral Mullen and Ambassador Pickering, oversaw a – Accountability Review Board which I think everyone is judging to have been quite – and the recommendations that they have made are being adopted in full, and there has already been, in this very short period of time, actions that demonstrate accountability is being upheld.


I don’t – I mean I haven’t had a discussion with the president, but I think he is both appreciative of Ambassador Pickering and Admiral Mullen for the service they provided to the nation here, for the depth that they delved into in this report and the seriousness of the recommendations, the speed with which they acted; and, you know, he intends to make sure that the administration, as the secretary of state has said, begins implementation of all of these recommendations before the next secretary of state takes office.


Some of this has to do – some of it will have to do with working with Congress to ensure that Congress provides the necessary funds to allow for enhanced security at our diplomatic missions around the world. So there is obviously more action that needs to be taken, but this is a very serious report and the president has indicated that he expects it to be implemented fully.


TAPPER: Again, I’m not disparaging the report. I’m just wondering if -


(Cross talk.)


CARNEY: Again, I think – I don’t have another answer for you. Four people have already, in one way or another, been held accountable, fairly senior people, so -


TAPPER: Is that sufficient for the president? That’s the only question.


CARNEY: I believe the president believes that the recommendations and the actions taken have been the right ones.


TAPPER: O.K., one other thing I wanted to ask about the mental health ramifications following Sandy Hook, and that is there have been some interesting personal stories in the media about parents – a lot of them single parents, but not exclusively – struggling with children who are mentally ill, some of them violently so, most of them not, who do not have enough help from society. They fall through some holes, some cracks in the system. I’m just wondering if the president has seen any of these, have read any of the – of the essays that have been written, and caught any of them on television, because it’s been – it’s actually been – it’s been remarkable to hear, because normally you don’t hear stories like this.


CARNEY: Well, I haven’t had that discussion with him. He is someone who reads widely, and it would surprise me if he hasn’t read or seen some of the reports that you’re talking about, probably more likely to have read rather than seen, with all due respect to the broadcast media.


But the fact is that he believes very strongly that mental health is one of the major areas that needs to be addressed as we take a kind of comprehensive approach to this problem. It’s why – setting aside the issue of gun violence – but the issue of mental health in general is extremely important to – in the president’s view, to our – what our overall approach to health care in this country ought to be, which is why, as you know, he made sure that the health care law that he passed with Congress will ensure 30 million more Americans have access to mental health services, and that will also – makes recommended mental health services available without a co-pay or a deductible – again, part of the effort here to make it clear that issues of mental health are as important, both for the individual and for the society, as issues of physical health.


So – but as it relates to the gun violence there is no question that this is something that needs more exploration and likely more action, which is why the president has taken the action that he has.


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Parenting/Kids News Headlines – Yahoo! News





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IntercontinentalExchange buys NYSE Euronext for $8 billion






NEW YORK/LONDON (Reuters) – IntercontinentalExchange struck an $ 8.2 billion deal to buy NYSE Euronext, a combination that will propel the commodities market powerhouse into European financial futures but threaten to further reduce the clout of the New York Stock Exchange.


The deal will create a new player in global derivatives trading and clearing that would take on CME Group Inc. While the New York Stock Exchange has stood for 200 years as an iconic symbol of U.S. capitalism, it is almost an afterthought in this deal.






Atlanta-based ICE said it will try to spin off the Euronext European stock market businesses in a public offering, generating speculation it may eventually shutter the NYSE‘s trading floor, as well. Profits from stock trading have been significantly eroded by new technology and the rise of private venues run by Wall Street banks and brokers.


Analysts said the deal will give ICE a strategic boost with control of Liffe, Europe’s second-largest derivatives market, helping it compete against U.S.-based CME Group, owner of the Chicago Board of Trade. Derivatives trading remains quite profitable for the exchanges and new rules coming into play next year will dramatically expand the demand for clearing over-the-counter contracts.


Regulatory concerns sank two deals to buy NYSE Euronext last year, including a joint bid by ICE and Nasdaq OMX Group and a separate bid from German exchange Deutsche Bourse. But ICE alone has far less overlapping business and should face easy approvals, antitrust attorneys said.


The deal values each NYSE Euronext share at $ 33.12, a 28 percent premium to the stock’s closing price on Wednesday. Shareholders will have the option of accepting $ 33.12 in cash per NYSE Euronext share or 0.2581 ICE share or a mix of $ 11.27 in cash and 0.1703 ICE share, subject to a maximum cash consideration of $ 2.7 billion..


NYSE Euronext stock rose 33 percent, to $ 31.88, after the deal was announced. ICE’s shares fell as much as 4 percent before clawing back some of the losses to trade down 0.6 percent, at $ 127.60, at 01:10 p.m. ET.


ICE said it would pay an annual dividend of $ 300 million once the deal closes.


NYSE Chief Executive Duncan Niederauer called the deal a “no brainer” on a call with analysts on Thursday. Further consolidation of exchanges was “inevitable” and ICE was a “great partner,” he said, so continuing on alone did not make sense.


“We can sit here and keep slugging away and keep working hard, but the bottom line is we had not delivered, in my mind, sufficient returns to shareholders,” Niederauer said.


Before the latest ICE offer emerged, NYSE Euronext‘s shares had fallen by nearly a third since ICE and Nasdaq launched their thwarted joint bid.


The newest offer first took shape in October when ICE Chairman and Chief Executive Jeff Sprecher, a consummate deal maker, called Niederauer to consider reviving their talks without the Nasdaq involved, said one person familiar with the situation who was not authorized to speak to the press.


ICE started out as an online marketplace for energy trading before Sprecher initiated a string of acquisitions from the London-based International Petroleum Exchange in 2001, to the New York Board of Trade and, most recently, a handful of smaller deals, including a climate exchange and a stake in a Brazilian clearing house.


A tie-up with Liffe would give Sprecher a boost to trade in to interest rates, one of the world’s biggest asset classes and a particular specialty of CME. Liffe and CME have a long-time rivalry in trading of short-term interest-rate contracts, with each launching – to little effect – look-alike versions of the other’s contracts. The CME declined to comment on the proposed deal.


“ICE is after Liffe, that is the crown jewel of NYSE Euronext,” said Peter Lenardos, analyst at RBC Capital Markets. NYSE bought Euronext, including Liffe, for 8 billion euros in 2007. “Strategically it makes sense for ICE to enter the European derivatives space in a meaningful way.”


ICE’s current main operations are in energy futures trading and, it has steered clear of stocks and stock-options trading, key businesses for NYSE Euronext. So there is not much business overlap between the two groups compared with last year’s proposed takeovers.


“This deal is probably not going to generate a lot of concern from an antitrust perspective,” said Warren Rosborough, a veteran of the U.S. Justice Department’s antitrust division who is now with the law firm McDermott Will & Emery.


A small amount of competing derivatives business could be addressed with straightforward divestitures, he said. “It’s an open question about whether it will generate questions,” he said. “If there is a fix, it will be relatively easy fix.”


Sprecher, who will be chairman and CEO of the combined company, said the deal had been “well received” by regulators after he and Niederauer completed a “whirlwind tour” in the United States and Europe ahead of Thursday’s announcement. Officials at the European Commission and the U.S. Securities and Exchange Commission declined to comment.


Last year, the Justice Department blocked a $ 11 billion joint hostile bid by ICE and Nasdaq OMX on concerns the tie-up would dominate U.S. stock listings. A rival $ 9.3 billion bid by Deutsche Boerse fell afoul of European regulators.


A combined ICE-NYSE Euronext would leap-frog Deutsche Boerse to become the world’s third-largest exchange group with a combined market value of $ 15.2 billion. CME Group has a market value of $ 17.5 billion, Thomson Reuters data shows.


Hong Kong Exchanges and Clearing is the world’s largest exchange group with a market cap of $ 19.5 billion.


ICE said it expected to achieve $ 450 million in cost savings from the takeover. In the first year after the deal closes, additional earnings of 15 percent are expected.


Long-time Wall Street traders saw the potential takeover of the venerable stock exchange by a 12-year-old derivatives upstart as weighted with symbolism.


“It’s the end of an era,” said a director on the board of a rival exchange who did not have clearance to speak to the press and asked not to be named. “I think ultimately the floor will be closed, because Jeff (Sprecher) has shut every floor he’s ever had,” the person said.


The exchange was prepared to shut down the floor temporarily during superstorm Sandy and trade completely electronically, Wall Street executives said.


But one former New York Stock Exchange executive was doubtful that ICE would completely shut down the NYSE floor. “It has too strong a marketing brand associated with it to close it,” said the executive, who declined to be identified because he is not permitted to speak to the press.


Morgan Stanley was the lead financial adviser to ICE, with assistance from BMO Capital Markets Corp, Broadhaven Capital Partners, JPMorgan Chase & Co, Lazard Group LLC, Societe Generale Corporate & Investment Banking, and Wells Fargo Securities LLC. ICE legal advisers are Sullivan & Cromwell LLP and Shearman & Sterling LLP.


The principal financial advisers to NYSE Euronext are Perella Weinberg Partners and BNP Paribas. Further financial advice to NYSE Euronext is being provided by Blackstone Advisory Partners, Citigroup, Goldman Sachs & Co. and Moelis & Co. Legal advisers to NYSE Euronext are Wachtell, Lipton, Rosen & Katz, Slaughter & May, and Stibbe NV.


(Additional reporting by Luke Jeffs and David Brough in London, Jessica Toonkel, Diane Bartz and Karen Brettell in New York, Sarah N. Lynch in Washington and Ann Saphir in Chicago; writing by Carmel Crimmins and Aaron Pressman; editing by Philippa Fletcher)


Business News Headlines – Yahoo! News





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Wounded presage health crisis for postwar Syria






ATMEH, Syria (AP) — A baby boy joined the ranks of Syria’s tens of thousands of war wounded when a missile fired by Bashar Assad‘s air force slammed into his family home and shrapnel pierced his skull.


Four-month-old Fahed Darwish suffered brain damage and, like thousands of others seriously hurt in the civil war, he will likely need care well after the fighting is over. That’s something doctors say a post-conflict Syria won’t be able to provide.






Making things worse, there has been a sharp spike in serious injuries since the summer, when the regime began bombing rebel-held areas from the air, and doctors say a majority of the wounded they now treat are civilians.


This week, Fahed was recovering from brain surgery in an intensive care unit, his head bandaged and his body under a heavy blanket, watched over by Mariam, his distraught 22-year-old mother.


She said that after her first-born is discharged from the hospital in Atmeh, a village in an area of relative safety near the Turkish border, they will have to return to their village in a war zone in central Syria.


“We have nowhere else to go,” she said.


Even for those who have escaped direct injury, the civil war is posing a mounting health threat. Half the country’s 88 public hospitals and nearly 200 clinics have been damaged or destroyed, the World Health Organization says, leaving many without access to health care. Diabetics can’t find insulin, kidney patients can’t reach dialysis centers. Towns are running out of water-purifying materials. Many of the hundreds of thousands displaced by the fighting are exposed to the cold in tents or unheated public buildings.


“You are talking about a public health crisis on a grand scale,” said Dr. Abdalmajid Katranji, a hand and wrist surgeon from Lansing, Michigan, who regularly volunteers in Syria.


No one knows just how many people have been injured since the uprising against Assad erupted in March 2011, starting out with peaceful protests that turned into an armed insurgency in response to a violent government crackdown.


More than 43,000 have been killed in the past 21 months, said Rami Abdul-Rahman, head of the Britain-based Syrian Observatory for Human Rights, basing his count on names and details provided by activists in Syria. He said the number of wounded is so large he can only give a rough estimate, of more than 150,000.


Casualties began to rise dramatically at the start of the summer. At the time, the regime, its ground troops stretched thin, began bombing from the air to prevent opposition fighters from gaining more territory.


Seemingly random bombings have razed entire villages and neighborhoods, driving terrified civilians from their homes, with an estimated 3 million Syrians out of the country’s population of 23 million now displaced.


About 10 percent of the wounded suffer serious injuries and many of those will need long-term care and rehabilitation, said Dr. Omar Aswad of the Union of Syrian Medical Relief Organizations, an umbrella for 14 aid groups.


This includes artificial limbs and follow-up surgery. “This is of course not available and will be one of the major (health) problems in the months right after the war,” said Mago Tarzian, emergency director for the Paris-based Doctors Without Borders.


For now, aid groups are struggling to provide even emergency treatment in under-equipped clinics.


The two dozen small hospitals and field clinics in rebel-run areas of Idlib province in the north only have a few Intensive Care Unit beds between them, said Aswad. None has a CT scanner, an important diagnostic tool.


“We need generators, we need medical supplies and the most pressing is medicine,” he said.


The challenge has been compounded by new types of injuries.


The regime has begun dropping incendiary bombs that can cause severe burns, according to the New York-based Human Rights Watch, citing amateur video and witness accounts.


Ole Solvang, a researcher for the group, said he saw remnants of such a bomb on a recent Syria trip. Aswad said doctors in Idlib and nearby Aleppo province reported seeing patients with burns from such weapons.


Doctors and hospitals have also been targeted. Aswad, who fled the city of Idlib in March after regime forces entered it, said five friends in a secret association of anti-regime physicians have been arrested. Hospitals, ambulances and doctors have been attacked, Solvang said, calling it “a worrying trend that makes the medical situation even worse.”


One of the bright spots is a 50-bed emergency care clinic set up six weeks ago in a former elementary school in Atmeh.


Largely funded by a wealthy Syrian expatriate, the Orient clinic, with five ICU beds, handles some of the most serious cases in a radius of some 150 kilometers (90 miles), said its director, orthopedic surgeon Abdel Hamid Dabbak.


In the past, seriously wounded patients had to go to Turkey, risking dangerous delays at the border, he said. Now, once patients are stabilized in Atmeh, they are sent to a sister clinic across the border for follow-up care.


In Orient’s ICU, a 24-year-old rebel fighter was breathing oxygen through a mask. He had been brought in a day earlier, bleeding heavily from stomach wounds and close to death, said Dr. Maen Martini, a volunteer physician from Joliet, Illinois. After surgery, he stabilized and was taken off a respirator. A delayed crossing into Turkey would have killed him, Martini said.


The fighter’s neighbor was little Fahed, whose house had been struck by a missile on Saturday in the village of Kafr Zeita in Hama province. “The roof collapsed on us,” his mother said of the attack. “We ran out … I saw him bleeding from his head, but it was just a small cut.”


The local clinic said the injury was more serious than it seemed and the family rushed to Atmeh, more than 100 kilometers (60 miles) to the north.


Since surgery, Fahed has been nursing and has moved his arms and legs, and the doctor is hoping for a near-complete recovery.


“Clinically, he has improved dramatically,” he said.


Middle East News Headlines – Yahoo! News





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Wii U finally gets Nintendo’s TVii service on December 20th






After a month-long delay, Nintendo (NTDOY) will launch its Nintendo TVii service for the Wii U on December 20th in the U.S. and Canada. Nintendo TVii is the company’s take on organizing all of the various video streaming and DVR services a user might subscribe to and then displaying them in an easy-to-navigate touchscreen-based interface on the Wii U GamePad. With Nintendo TVii, Nintendo hopes to make content discovery an easier task, rather than a chore. At the same time, Nintendo TVii will offer new “second-screen” experiences (similar to Xbox SmartGlass) with built-in social sharing options to Facebook (FB), Twitter and the Wii U console’s Miiverse.


[More from BGR: BlackBerry 10 browser smokes iOS 6 and Windows Phone 8 in comparison test [video]]






[More from BGR: LG’s woeful comeback attempt]


Nintendo TVii will support Amazon (AMZN) Instant Video, Hulu Plus and cable and satellite providers on Thursday, but Netflix (NFLX) and TiVo (TIVO) support won’t hit the U.S. until “early 2013.” Nintendo didn’t state when TVii support for the latter two will hit Canada.


For the consumer’s sake, we hope the download for Nintendo TVii doesn’t take as long as past system updates.


Nintendo’s press release follows below.



Nintendo Makes TV Smart and Social – Nintendo TVii Launches Dec. 20


New Wii U Service Gives Every Member of the Family His or Her Own Personalized, Easy-to-Use Second-Screen Viewing Experience


REDMOND, Wash.–(BUSINESS WIRE)–The company that changed how we play is about to change how we watch. On Dec. 20, Nintendo will introduce Nintendo TVii, a free, integrated service for the recently launched Wii U console that combines what you watch and how you watch into one seamless, second-screen experience on the revolutionary new Wii U GamePad controller.


The rapid increase in both the quality and availability of video entertainment content – hundreds of satellite and cable channels, a seemingly endless amount of video-on-demand options – has made finding something to watch a complex and occasionally frustrating process. The solution to this problem is coming from perhaps an unexpected place: a video game console.


“After Dec. 20, you’ll never look at your TV the same way again,” said Nintendo of America President and COO Reggie Fils-Aime. “Wii U owners have already experienced the transformative effect that the GamePad has on game play and social interaction. Nintendo TVii shows how the integrated second screen of the GamePad can also transform and enhance the TV viewing experience. Welcome to the new world of TVii.”


Nintendo TVii maximizes Wii U owners’ current cable, satellite and video-on-demand services by pulling all of their available content sources – such as a Comcast cable package or Hulu Plus subscription – into one place. This empowers Wii U owners to focus on whatthey want to watch and not how they want to watch. And once users find the show, sporting event or movie they want, they press an icon and Nintendo TVii does the rest.


In addition to greatly simplifying finding and watching video content, Nintendo TVii also includes a series of social features that enable Wii U owners to share experiences and exciting moments with friends as they are happening on live TV. People can engage with others by commenting and sharing on Miiverse, Facebook and Twitter. Or they can comment, post or tweet about an incredible touchdown, a remarkable performance or a shocking plot twist, all using the personal screen of the Wii U GamePad.


Nintendo TVii requires no additional equipment and can be enjoyed with very little setup, demonstrating what’s possible when the second screen is truly integrated with the TV. Wii U owners can also discover more information about what they’re watching by easily accessing information on the GamePad via an Internet connection, including cast details, movie reviews from Rotten Tomatoes and sports data such as live stats and scores.


Nintendo TVii launches in the United States and Canada on Dec. 20. At launch, the service will support cable and satellite providers in both regions, as well as direct integration with Amazon Instant Video and Hulu Plus subscriptions in the United States. Further integration with Netflix subscriptions and TiVo are expected in early 2013 in the United States. Wii U owners with a Netflix subscription can still access the Netflix application from the Wii U system’s main menu and enjoy their favorite content accordingly.


All elements of the Nintendo TVii service are included in the purchase price of the Wii U system. Users will define which services they currently subscribe to – including the channel lineup in their cable package and video-on-demand service subscriptions – as part of the setup process.


Nintendo TVii observes the Wii U system parental controls, and additional options specific to the Nintendo TVii features can be chosen in the Nintendo TVii settings. Every member of the family can create a different viewing profile. For more information about this and other features, visit http://www.nintendo.com/wiiu.



This article was originally published by BGR


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Madonna leads Billboard’s top-grossing tours






LOS ANGELES (Reuters) – While this year’s pop charts have been dominated by young singers, it is veteran music stars, led by Madonna, who are commanding big money in tour ticket sales, according to a new Billboard list released on Tuesday.


Madonna, 54, topped Billboard‘s list of highest-grossing live tours, earning an estimated $ 228.4 million in ticket sales from her sold-out ninth worldwide tour in support of her 12th studio album “MDNA.” The singer will wrap her tour in South America this weekend, after performing more than 80 shows across the world starting in Israel in May.






Madonna came ahead of pop star Lady Gaga, who landed at No. 6, with ticket sales of $ 124.9 million from her worldwide “Born This Way Ball” tour. Gaga, 26, is currently midway through her tour, which kicked off in South Korea in April, and will wrap in Oklahoma in March 2013.


Music publication Billboard compiled its list through estimated gross ticket sales figures from Billboard box scores, which tracks concert tours, ticket prices and sales.


The top five highest-grossing tour acts of 2012 included Bruce Springsteen, 63, and the E Street band at No. 2 with $ 199 million from 72 shows and Pink Floyd’s Roger Waters, 69, at No. 3 with $ 186 million.


Cirque Du Soleil‘s homage to late singer Michael Jackson in “The Immortal World Tour” ranked No. 4 with $ 147.3 million over 183 shows, and British rock band Coldplay was fifth with $ 147.2 million over 67 shows.


The only other young stars in the list of 25 top-grossing tours was Canadian pop star Justin Bieber, 18, at No. 20 with $ 30 million from 29 shows as part of his ongoing “Believe” tour, and country-pop darling Taylor Swift, 23, who raked in $ 26 million from 21 shows from her “Speak Now World Tour.”


Last year, Swift ranked No. 5 on Billboard‘s list with an estimated $ 97 million in ticket sales from her “Speak Now World Tour,” while Bieber came in at No. 15 with $ 44 million.


Swift will embark on her third worldwide concert tour in support of her studio album “Red” in March 2013.


(Reporting By Piya Sinha-Roy; Editing by Patricia Reaney and Eric Walsh)


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Amgen pagará 762 millones por vender un medicamento para usos no autorizados






Nueva York, 19 dic (EFE).- El gigante estadounidense de la biotecnología Amgen pagará una sanción de 762 millones de dólares tras declararse culpable de introducir en el mercado un medicamento para usos no permitidos por las autoridades federales.


La compañía aceptó hoy en un tribunal federal de Brooklyn (Nueva York) un acuerdo para declararse culpable, clausurar el caso y pagar 150 millones en sanciones criminales y 612 millones para cubrir las solicitudes de compensación a programas públicos de seguro médico, como Medicare o Medicaid.






El caso se refiere al “Aranesp”, un medicamento aprobado por la Administración de Fármacos y Alimentos (FDA, por sus siglas en inglés) para favorecer la formación de glóbulos rojos en los tratamientos de anemias.


“A fin de incrementar las ventas de Aranesp y lograr más beneficios, Amgen ilegalmente vendió el medicamento con la intención de que se usara con dosis que la FDA había estudiado y rechazado, y para tratamientos que la FDA nunca aprobó”, señaló el tribunal federal en un comunicado.


El acuerdo supone la mayor sanción por fraude a una compañía de biotecnología en la historia de Estados Unidos.


El fiscal federal Marshall Miller señaló que “en lugar de trabajar para alargar y mejorar la vida humana, Amgen buscó ilegalmente los beneficios empresariales mientras ponía en peligro la seguridad de consumidores vulnerables que sufrían enfermedades”. EFE


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